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Reuters Business News

  • SEC to propose new rules for money-market funds: WSJ
    (Reuters) - The Securities and Exchange Commission (SEC) will unveil proposals aimed at stabilizing money-market funds in the event of another financial panic, the Wall Street Journal reported on Tuesday, citing people familiar with the matter.
  • Markets edge down as Greece wrangling tempers momentum
    TOKYO (Reuters) - Markets edged down on Tuesday as Greek resistance to the strict conditions attached to a bailout fund sapped recent momentum spurred by hopes the global economy is improving, and the euro eased on renewed fears of a messy debt default.
  • Facebook governance a concern for California pension fund
    NEW YORK (Reuters) - Facebook's corporate governance rules, which give shareholders little say in how the social networking website would be run as a public company, are raising the hackles of one of the largest U.S. investors, the California State Teachers' Retirement System.

Nature Medicine

  • Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass
    Targeting mesenchymal stem cells (MSCs), progenitors of osteoblasts, to bone has been a long-standing goal but has had limited success so far. Here, Min Guan and her colleagues deliver a peptidomimetic integrin ligand against integrin α4β1 conjugated to the bone-seeking agent bisphosphonate alendronate as a means of attracting infused and/or endogenous MSCs to the bone surface to stimulate bone formation. The approach was tested in both xenotransplantation and immunocompetent mice, as well as in mouse models of trabecular bone loss induced by aging and estrogen deficiency (ovariectomy).
  • Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis
    BMP7 has been previously shown to protect against renal fibrosis. Raghu Kalluri and his colleagues have now identified activin-like kinase 3 (Alk3) as the key co-receptor for BMP7 in the kidney and have identified an orally available, small-peptide agonist of Alk3 that reduces established fibrosis in five animal models of kidney injury.